![]() ![]() #5th mtp joint pain trialA randomized controlled trial of foot orthoses in rheumatoid arthritis. Foot pain in rheumatoid arthritis prevalence, risk factors and management: an epidemiological study. Otter SJ, Lucas K, Springett K, Moore A, Davies K, Cheek L, Young A, Walker-Bone K. Longitudinal follow-up is required to determine the mechanism and presentation of plantar plate pathology in the painful forefoot of patients with RA.Įrosion Foot Magnetic resonance imaging Metatarsophalangeal joint Plantar plate Rheumatoid arthritis. The distribution of plantar plate pathology at the lesser MTP joints in healthy control subjects differs to that seen in patients with RA who have the consequence of inflammatory disease in the forefoot. The presence of plantar plate pathology was independently associated with an increase in the odds of erosion (OR = 52.50, p < 0.001). No substantive or statistically significant associations were found between plantar plate pathology and clinical and biomechanical findings. There were significant differences between control subjects and patients with RA in the presence of plantar plate pathology at the lesser MTP joints. Multivariable multilevel modelling was used to assess the association between plantar plate pathology and the clinical, biomechanical and plain radiography findings. Plantar plate pathology in patients with RA was compared with control subjects. Images were read prospectively by two radiologists and consensus reached. Intermediate weighted fat-suppressed sagittal and short axis sequences were acquired through the lesser MTP joints. ![]() In 41 patients with RA and ten control subjects the forefoot was imaged using 3T MRI. Secondly, to compare plantar plate pathology at the symptomatic lesser (2nd-5th) MTP joints in patients with RA, with a group of healthy age and gender matched control subjects without foot pain. The aims of this study were to investigate the relationship between plantar plate pathology and clinical, biomechanical and plain radiography findings in the painful forefoot of patients with RA. Damage to the plantar plates is a plausible mechanism therefore, through which the forefoot presentation, commonly described as 'walking on pebbles', may develop in patients with RA. Together with the transverse metatarsal ligament they prevent splaying of the forefoot and subluxation of the MTP joints. The plantar plates are the fibrocartilaginous distal attachments of the plantar fascia inserting into the five proximal phalanges. The forefoot is widely affected and the metatarsophalangeal (MTP) joints are the most common site of symptoms. Disease-related foot pathology is recognised to have a significant impact on mobility and functional capacity in the majority of patients with rheumatoid arthritis (RA). ![]()
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![]() In the fourth season, hundreds of nuclear reactors around the world are melting down due to decades of neglect that will result in the majority of the planet becoming uninhabitable. is ultimately destroyed by Clarke, but not before warning of another impending apocalyptic disaster. A.L.I.E. – who was commanded to make life better for mankind – is revealed to have responded by solving the problem of human overpopulation by launching the nuclear apocalypse that devastated Earth, and begins to use ingestible computer chips to take control of peoples' minds. Furthermore, the grounder leader Lexa is killed by her mentor during a failed assassination attempt on Clarke. Pike kills an encampment of grounder warriors while they sleep, which further damages their already fragile relationship with the grounders. In the third season, Alpha Station renamed Arkadia, comes under new management when Pike, a former teacher, and mentor on the Ark, is elected as chancellor and begins a war with the grounders. while John Murphy finds an alarming video implying a connection between the AI and the destruction of the world. ![]() During this time, former Chancellor Jaha leads a group in search of a fabled "City of Light." Jaha discovers an artificial intelligence named A.L.I.E. The season ends with the massacre of the Mountain Men to save the prisoners. Meanwhile, the inhabitants of the Ark have crash-landed various stations on Earth and begin an alliance with the grounders to save both their people, naming the main settlement at Alpha Station "Camp Jaha". Medical tests of the forty-eight show their bone marrow will allow the Mountain Men to survive outside containment, so the Mountain Men begin taking the youths' bone marrow. The Mountain Men are transfusing blood from imprisoned grounders as an anti-radiation treatment as their bodies have not adapted to deal with the remaining radiation on Earth. In the second season, forty-eight of the remaining detainees are captured and taken to Mount Weather by the Mountain Men. Under the leadership of Bellamy and Clarke, the juveniles attempt to survive the harsh surface conditions, battle hostile grounders and establish communication with the Ark. They discover that some survived the apocalypse: the Grounders, who live in clans locked in a power struggle the Reapers, another group of grounders who have been turned into cannibals by the Mountain Men and the Mountain Men, who live in Mount Weather, descended from those who locked themselves away before the apocalypse. Three generations have been born in space, but when life-support systems on the Ark begin to fail, one hundred juvenile detainees are sent to Earth in a last attempt to determine whether it is habitable, or at least save resources for the remaining residents of the Ark. Ninety-seven years after a devastating nuclear apocalypse wipes out almost all life on Earth, thousands of people now live in a space station orbiting Earth, which they call the Ark. Abby Griffin ( Paige Turco), Clarke's mother Marcus Kane ( Henry Ian Cusick), a council member on the Ark and Thelonious Jaha ( Isaiah Washington), the Chancellor of the Ark. The main cast of juvenile prisoners includes Clarke Griffin ( Eliza Taylor), Finn Collins ( Thomas McDonell), Bellamy Blake ( Bob Morley), Octavia Blake ( Marie Avgeropoulos), Jasper Jordan ( Devon Bostick), Monty Green ( Christopher Larkin), Raven Reyes ( Lindsey Morgan), and John Murphy ( Richard Harmon). They are among the first people from a space habitat, the Ark, to return to Earth after a devastating nuclear apocalypse. ![]() The 100 season 6 netflix release series#The series follows a group of post-apocalyptic survivors, chiefly a group of criminal adolescents. The series, developed by Jason Rothenberg, is loosely based on the young adult novel series of the same name by Kass Morgan. The 100 (pronounced The Hundred ) is an American post-apocalyptic science fiction drama television series that premiered on March 19, 2014, on The CW and ended on September 30, 2020. ![]() ![]()
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